| M13 phage structure | Serving as a powerful tool for high-throughput screening of molecular interactions, phage display has been proven the most popular among all available display techniques. By the genetic manipulation of genes of surface proteins on filamentous phages, target of interest will be expressed on the surface of phage to support the biopanning. Instead of intact phage, current phage display systems employ various bacteriophage vectors, including filamentous M13, T7, bacteriophage lambda (λ phage) and T4 phage display systems. Creative Biolabs has developed the most comprehensive phage display systems for customized projects to meet your specific requirements. |
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M13 phage structure
| Ligand-linker conjugate | An intact PROTAC molecule consists of 3 components, a ligand for target proteins, a linker, and a ligand against E3 ubiquitin ligase. Ligand-linker conjugates are chemical molecules that a linker molecule linked to the ligand against target proteins or against the E3 ubiquitin ligase. The binding affinities may be altered by additional chemical structures, therefore, with this type of product, the properties of ligands and linkers could be evaluated at the same time and have much close results with an intact PROTAC molecule. Besides, with the same functional ligands conjugated with different linkers, the compounds have advantages in functional comparison and subsequent screening. In addition, the ligand-linker conjugates decrease the amount of time spent on PROTACs synthesis. Below Creative Biolabs listed alkyl-chains, PEGs, alkyl/ethers linked ligand-linker conjugates with various ligands. All these partial PROTAC molecules have high solubility in DMSO or other appropriate solvents. |
| coronavirus Cytopathic Effect Assay development | SARS-CoV-2, a novel coronavirus strain, has spread to almost every country in the world and thus become a major public health concern. Researchers all over the world are trying their best to improve the current situation in different methods. Cytopathic Effect (CPE) assay is one of the antiviral tests that may help with discovering more information about SARS-CoV-2. As a socially responsible company focused on antiviral research, Creative Biolabs has been committed to SARS-CoV-2 and relative studies since it broke out. With advanced technology and mature researchers, we provide global clients with reliable CPE assay services to promote the study of SARS-CoV-2. |
| Recombinant ARHGDIA Protein aa 24-204 His Human origin | Creative Biolabs provides high quality products and services to the global biology researcher at inception as their lofty mission. After more than ten years of innovation and development, we have grown into a prestigious CRO in the industry. In addition to providing researchers with various products such as recombinant proteins, antibodies, and test kits, we have also accumulated a lot of experience in drug discovery and vaccine development. Especially in the field of antiviral drugs and vaccines, our drug discovery, vaccine design, preclinical evaluation of drugs and vaccines, and in vitro diagnostic services are at the world-leading level. |
| single domain antibodies peptide | Creative Biolabs is one of the well-recognized experts who are professional in high-quality antigen design and preparation. The selection of proper antigen is one of the most critical steps for a successful single domain antibody (sdAb) development project. According to the different targets and expected applications, antigens may need to be designed and prepared in a variety of formats. With over ten years’ extensive experience and advanced antigen preparation platforms, our scientists are confident in designing the best-fit antigens for your project and preparing them in a high-quality manner. |
| Single cell RNA-seq for Natural Killer Cells | NK cells are potent cytotoxic lymphocytes that provide critical host defense against pathogens and malignancy. As an unparalleled single cell omics service provider, Creative Biolabs provides transcriptome, epigenetic and proteomics analysis services for NK cells at single-cell level. |
| Single Cell RNA Expression Profiling to COVID-19 | Single-cell sequencing and analyses have been applied in the field of virology, providing new approaches to explore viral diversity and cell response to viral infection, including the widely-spreading SARS-CoV-2 (COVID-19). Empowered by unrivaled expertise and advances in single-cell approaches, Creative Biolabs has developed integrated single cell omics solutions to study differences between host cell types and subpopulations which are associated with virus entry and transmission, at single-cell level of genome, transcriptome, epigenome, and proteome. |
| Class-specific Aflatoxins Haptens | Creative Biolabs has an entrepreneurial team of highly-skilled and qualified experts in hapten design and synthesis. The members have originated from a rich academic research background, bringing their experience into translation. We are very proud of providing high-quality, omnidirectional hapten discovery services targeting 3-Amino-2-oxazolidinone (AOZ) for our valued clients to remove the difficulties of your projects. Up to now, we have also generated a novel platform to design, synthesize, evaluate, and modify potential haptens for AOZ. This platform has been considered as an attractive strategy for producing small molecule haptens for AOZ with high specificity and affinity. |
| Design and Synthesis of Compound-specific Haptens (Aring /B ring) for Steroid Hormones | Steroid hormone haptens will not be able to stimulate the animals to produce specific antibodies directly. However, they can be modified to introduce an accessible functional group as well as a connecting arm and then combined with a macromolecular carrier, such as a protein, and in turn, they can induce strong immune responses to produce anti-hapten antibodies. With years of experience in antigen design and antibody development, Creative Biolabs holds specific expertise in the design and synthesis of haptens and coupling of haptens to a best-fit carrier, as well as subsequent preparation of anti-hapten antibodies. |
| iPSC-derived NK cell generation assays | Creative Biolabs provides high quality transcription-activator-like effector nuclease. Please contact us if you need more information. |
| MSC Immunophenotype | Creative Biolabs provides high quality transcription-activator-like effector nuclease. Please contact us if you need more information. |